PeptideDB

7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene

CAS: 1159977-58-8 F: C42H44N2O6S W: 704.87

7-benzoyl Raloxifene is a liver receptor homolog-1 (LRH-1) antagonist with an IC50 of 3.1 μM.
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Bioactivity 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is a liver receptor homolog-1 (LRH-1) antagonist with an IC50 of 3.1 μM[1].
Invitro 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is binding to the domain (LBD) of LRH-1[1].
Name 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene
CAS 1159977-58-8
Formula C42H44N2O6S
Molar Mass 704.87
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Rey, J., et al. Discovery of a New Class of Liver Receptor Homolog-1 (LRH-1) Antagonists: Virtual Screening, Synthesis and Biological Evaluation. ChemMedChem,2012; 7(11), 1909–1914.